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CAR-T Cells
Very promising cellular therapy, which exists to combat some B Lymphomas, Acute Lymphoid Leukemia and Multiple Myeloma.
What is it?
T cells or lymphocytes are part of the immune system and their main function is to protect the body against infections, but they can also fight cancer cells.
This therapy consists of genetically modifying these T cells, making them recognize tumor cells and destroy them. In this way, the patient's own body becomes a treatment against cancer.
This is an innovative treatment that has shown important results, offering a new option in some types of cancer.
What types of cancer can it be used for?
Used to treat certain types of B-cell lymphomas, acute lymphocytic leukemia, and multiple myeloma. In solid tumors, there are some studies being developed.
In Brazil we have CAR-T cells for Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Primary Mediastinal Lymphoma, Acute Lymphoid Leukemia and Multiple Myeloma.
What are the possible side effects?
One of the most common and serious side effects is cytokine release syndrome. This occurs when the immune system responds to the infused CAR-T cells more aggressively than it should. Neurological toxicity may also occur, in addition to infections.